浙江大學(xué)的葉老師領(lǐng)導(dǎo)下的研究團(tuán)隊(duì)，應(yīng)用美國FIAlab公司生產(chǎn)的FIAlab-3500順序注射分析儀研究開發(fā)出一款平面多電極陣列神經(jīng)元芯片嗅覺感受器，有關(guān)該產(chǎn)品的介紹文章已發(fā)表在2010年9月的生物傳感器與生物電子學(xué)雜志上為了大家學(xué)習(xí)參考，現(xiàn)將她刊登在我公司的網(wǎng)站上 Abstract A novel olfactory neurochip based on olfactory receptor neurons (ORNs) cultivated on the surface of the 60-channel planar multi-electrode array (MEA) devices was developed in this study. In order to investigate the odor-response characteristics of ORNs, two types of odorants at different concentrations were quantitatively pumped into the neurochip by a customized gas intake system, and the extracellular electrical activities of multiple ORNs were simultaneously recorded in vitro. Accordingly, the odor-response features of ORNs such as firing amplitude, firing threshold, firing rate as well as firing channels were analyzed qualitatively and quantitatively in terms of ORN spike trains. Especially, after introducing the classification algorithm based on the spike threshold, the odor-response maps from the multiple sites could be used to identify dl-limonene (LIM) and isoamyle acetate (ISO) odorants. These preliminary studies indicate that the ORN-based biosensor developed here has a potential capability of distinguishing different odorants as a true bionic electronic nose. FIAlab-3500 順序/流動(dòng)注射分析儀